According to the Centers for Disease Control and Prevention, it affects about 1 baby in every 700 births. Learn more about the causes, symptoms, and treatment of Klinefelter syndrome. Turner syndrome is a chromosomal disorder that affects only females. (i) Turner’s Syndrome results from the union of an abnormal (o) egg with a normal X sperm or a normal X egg and abnormal (o) sperm. Aneuploidy can be seen in human as genetic disorders; for example, Tuner syndrome, Klinefelter syndrome and Down syndrome, whereas polyploidy is common in plants. Turner syndrome is an example of monosomy while Down syndrome is an example of trisomy. Children with Down’s syndrome need to be explicitly taught the difference between the two, so it’s good to start early. Most men inherit a single X chromosome from their mother, and a single Y chromosome from their father. Now customize the name of a clipboard to store your clips. Klinefelter's syndrome is caused by the presence of an additional X chromosome in males and it manifests itself as a disorder of the endocrine system (Zitzmann et al., 2004). The chance a baby with Down syndrome increases with the age of the mother, however, 80 percent of babies with Down syndrome are born to 35 years old or younger women, simply because women in that age group have the most babies. Down syndrome: It is caused by the extra 21 chromosome that is present in an offspring. We report here results of endocrine, cytogenetic, and in vitro testicular steroidogenesis studies in a 19-year-old man with a 48,XXY,G + chromosome constitution, who lacked many of the classical features of Down or Klinefelter syndromes. Down syndrome or Mongolism is autosomal disorder and turner and klinefelter's syndrome are sex chromosomal disorder caused due to non disjunction. Jsorr 13:52, 8 March 2009 (UTC) Maybe adding language to the text indicating that Down syndrome is the most common extra-chromosome condition, while Klinefelter's is the most common sex-chromosome condition, would be in order. Children with Down’s syndrome really benefit from having friends who also have Down’s syndrome and also friends who are typically developing; having a foot in both camps. Individuals with this syndromes are phenotypically males but with tendency towards femaleness. Down syndrome affects people of all economic, educational, cultural, ethnic and racial categories. From the Department of Medicine, Montefiore Hospital (Drs. They show some abnormal features such as enlarged breasts, underdeveloped body hair, and small testes and prostrate glands. 1977; Pétremand‐Hyvärinen 1978).Klinefelter's syndrome (KS) is the most common chromosomal abnormality in humans. It involves a lack of part or all of a second sex chromosome in some or all cells. For example, lymphocytic leukemia is the result of cells containing 3 sets of chromosome 12. A woman with Turner syndrome is found to be colorblind (an X-linked recessive phenotype). They may have special medical problems of the heart, stomach, eyes, and other parts of the body. Aneuploidy can be seen in human as genetic disorders; for example, Tuner syndrome, Klinefelter syndrome and Down syndrome, whereas polyploidy is common in plants. Turner syndrome is the complete or partial monosomy of the X chromosome, which is characterized primarily by the hypogonadism in phenotypic females. Oct 2, 2019 - Explore Fatima hussain's board "project ideas .." on Pinterest. Instead of splitting cleanly into the two identical chromosomes, the newly divided chromosome will have extra genetic material. Variants of Klinefelter syndrome (such as 48,XXXY, 49,XXXXY) are much rarer, occurring in 1 in 50,000 to 1 in 85,000 or fewer newborns. Klinefelter syndrome, disorder of the human sex chromosomes that occurs in males, one of the most frequent chromosomal disorders in males. People with translocation Down syndrome still share the same health issues and learning problems with people with other types of Down Syndrome. (ii) Klinefelter’s Syndrome results 47 chromosomes and is a sterile male, obesity , mental retardation. The differences between Down syndrome and Klinefelter syndrome are as follows: Down syndrome: It is caused by the extra 21 chromosome that is present in an offspring. Many conditions can occur when a defective gene is inherited. One difference between sperm cells and ova is that: ova carry an X chromosome, whereas sperm carry either an X or a Y chromosome. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. In males a white man aged 19 years 3 months was referred of... 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